The Sanford Guide to HIV/AIDS and Viral Hepatitis Therapy Book PDF, ePub eBook

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Book Descriptions:

The Sanford Guide to HIV/AIDS and Viral Hepatitis Therapyis in its 22nd edition in print for 2014. This edition reflects the continuing evolution of HIV to a manageable chronic disease, at least in parts of the world with access to the latest antiretroviral drugs. New agents, new once-daily combination ARV drug formulations and new guidelines on pre-exposure prophylaxis (PrEP) are included. ART recommendations have been updated in accordance with the most recent sets of guidelines and the section on HIV diagnostics has been revised to include newly available tests. We have done a major revision of complications of ART, AIDS-related complications, and opportunistic infections to reflect the changing understanding and management of HIV.

We have significantly expanded our coverage of diagnosis and treatment of Hepatitis B and Hepatitis C virus infections. In many ways, the rapid development of novel treatments of HCV mimic remarkably the explosion of new drugs for HIV that emerged in the mid-1990s, constituting the HAART revolution. For the first time in over 20 years, outside of the release of pegylated interferon, completely new drugs are approved for use in patients with HCV infection. These new direct acting agents have improved the sustained virologic response (SVR), or cure, rate for HCV genotype 1 infections to levels unimaginable just 5 years ago. What's more, there are over 30 other new anti-HCV specific drugs in development that will further revolutionize the treatment of HCV over the next decade. This edition of the Guide provides an updated listing of these new agents in development.

Contents
• LIST OF FIGURES
• ABBREVIATIONS<
• JOURNALS AND OTHER REFERENCES<
• TABLE 1A Prophylactic Antiretroviral Therapy Reduces HIV Transmission Risk
• TABLE 1B Assessment of HIV Infection Risks & Recommendations for HIV Testing
• TABLE 2 Initial Evaluation of HIV-Infected Adult Patient
• TABLE 3A Laboratory Diagnosis Of HIV Infection—Antibody Tests, Western Blot Confirmation & HIV RNA Quantitation
• TABLE 3B CD4/CD8 T-Lymphocyte Counts In HIV Patients
• TABLE 3C Antiretroviral Drug Resistance Testing In HIV Infection
• TABLE 3D Diagnosis of Human T-Lymphotropic Virus (HTLV-1, HTLV-2)
• TABLE 4A 1993 Revised CDC HIV Classification System & Expanded AIDS Surveillance Definition for Adolescents & Adults
• TABLE 4B Correlation of Complications with CD4 Cell Counts/WHO Clinical Staging System
• TABLE 5A Rapid Oral TMP/SMX Desensitization
• TABLE 5B Methods for Penicillin Desensitization
• TABLE 6A Antiretroviral Therapy (ART) in Treatment-Naïve Adults (Regimens, Dosing)
• TABLE 6B Antiretroviral Drugs & Adverse Effects
• TABLE 6C Drug Adverse Effects by Clinical Presentation
• TABLE 6D Overlapping Toxicities Between Antiretrovirals and Other Drugs Commonly Used in HIV Patients
• TABLE 6E Anti-HIV Drugs Available Via Expanded Access Programs
• TABLE 6F Management of Antiretroviral Therapy Failure
• TABLE 6G Antiretrovirals Approved or Tentatively Approved by FDA for International AIDS Relief
• TABLE 6H Liquid Formulations of ART Drugs
• TABLE 6I Antiretroviral Drug Cost Comparison
• TABLE 7A Acute HIV Infection
• TABLE 7B Management of Exposure to Hepatitis B/C
• TABLE 7C HIV Exposure Management
• TABLE 8A HIV/AIDS In Women/Pregnancy
• TABLE 8B HIV in the Fetus & Newborn
• TABLE 8C HIV Infection in Children
• TABLE 8D Children: Initial Evaluation, Initiation of Antiretroviral Therapy, PJP Prophylaxis & Supportive Therapy
• TABLE 8E Clinical Syndromes, Opportunistic Infections in Infants & Children, which Differ from Adults
• TABLE 8F Selected Drugs Commonly Used in Children with HIV Infection
• TABLE 8G Prophylaxis for First Episode of Opportunistic Disease in HIV-Infected Infants & Children
• TABLE 9A Epidemiology of Hepatitis C (HCV)
• TABLE 9B Diagnosis of HCV Infection
• TABLE 9C Natural History of HCV
• TABLE 9D Clinical Presentation of Hepatitis C Infection
• TABLE 9E HCV Treatment Regimens and Response
• TABLE 9F HCV Drugs in Development
• TABLE 9G Epidemiology of Hepatitis B (HBV)
• TABLE 9H Natural History of HBV
• TABLE 9I Hepatitis B (HBV), Clinical Presentation
• TABLE 9J HBV Treatment
• TABLE 10 Primary Prophylactic Antimicrobial Agents Against Opportunistic Pathogens in Adolescents & Adults
• TABLE 11A Diagnosis & Differential Diagnosis of Clinical Syndromes, Opportunistic Infections & Neoplasms
• TABLE 11B Immune Reconstitution & Novel Syndromes Associated with ART
• TABLE 12 Treatment of Specific Infections in HIV+/AIDS Patients
• TABLE 13 Drugs Used in Treatment &/or Chronic Suppression of AIDS-Related Infections: Adverse Effects, Comments
• TABLE 14A Selected Pharmacologic Features of Antimicrobial Agents Used in HIV-Associated infections in Adults
• TABLE 14B Cytochrome P450 Interactions of Antimicrobials
• TABLE 15A Dosage of Antimicrobial Drugs in Adult Patients with Renal Impairment
• TABLE 15B No Dosage Adjustment with Renal Insufficiency
• TABLE 15C Dosage of Antiretroviral Drugs in Patients with Impaired Hepatic Function
• TABLE 16A Drug/Drug Interactions: Antiretroviral Drugs & Drugs Used in Treatment of HIV-Associated Infections & Malignancies
• TABLE 16B Drug-Drug Interactions Between Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTIs), Protease Inhibitors, CCR-5 Antagonist
• TABLE 17 Antimicrobics in Pregnancy
• TABLE 18 Spectrum & Treatment of HIV/AIDS-Associated Malignancies
• TABLE 19 Recommendations for Routine Immunization of HIV+ Children
• TABLE 20 Immunization of HIV+ Adults (Asymptomatic & Symptomatic)
• TABLE 21A Measures to be Taken by Physicians in Preparing HIV+ Patients & Individuals Likely to Have "Risky" Behavior for Overseas Travel
• TABLE 21B Immunization of HIV+ Adults Traveling to Developing Countries
• TABLE 22 Biologics in Treatment of Hematocytopenias
• TABLE 23 AIDS Information & Referral Services
• TABLE 24 List of Generic & Common Trade Names
• INDEX

The Sanford Guide to HIV/AIDS and Viral Hepatitis Therapy by Michael S., Ed. Saag, Henry F. Chambers, George M. Eliopoulos

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